HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenethyl bromide → 1-(3-Cyclopentylpropyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenethyl bromide | HCID 7666 | — |
| Edukt | 1-(4-Methoxyphenyl)-piperazine, dihydrochloride | HCID 2723700 | — |
| Edukt | 3-Cyclopentylpropyl methanesulfonate | HCID 23111435 | — |
| Edukt | 1-(2,5-Difluoro-4-methoxyphenyl)piperazine | HCID 23111492 | — |
| Produkt | 1-(3-Cyclopentylpropyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine | HCID 23111395 | — |
Reaktionsschritte
Production Example 1 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and (2-bromoethyl)-benzene were replaced with 1-(2,5-difluoro-4-methoxyphenyl)-piperazine (342 mg) and 3-cyclopentylpropyl methylsulfonate (309 mg), respectively, to provide crude 1-(3-cyclopentylpropyl)-4-(2,5-difluoro-4-methoxyphenyl)piperazine (486 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07449466B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-4354032514ac42e6a155f6e50c6a0ce8 |
| Quellennotiz | uspto-grants-2008_11 |