Phosphorus oxychloride → 7-[2-(2-Formamidothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-t-butoxycarbonylaminomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid

Reaktionsgleichung

[NH2:1][CH:2]1[C:28](=[O:29])[N:4]2[C:5]([C:25]([OH:27])=[O:26])=[C:6]([CH2:9][S:10][C:11]3[S:12][C:13]([CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])=[N:14][N:15]=3)[CH2:7][S:8][C@H:3]12.C[Si](CC(N)=O)(C)C.C[Si](C([Si](C)(C)C)C(N)=O)(C)C.P(Cl)(Cl)(Cl)=O.[CH:55]([NH:57][C:58]1[S:59][CH:60]=[C:61]([C:63](=[N:67][O:68][CH3:69])[C:64](O)=[O:65])[N:62]=1)=[O:56]>C(OCC)(=O)C.CN(C)C=O>[CH:55]([NH:57][C:58]1[S:59][CH:60]=[C:61]([C:63](=[N:67][O:68][CH3:69])[C:64]([NH:1][CH:2]2[C:28](=[O:29])[N:4]3[C:5]([C:25]([OH:27])=[O:26])=[C:6]([CH2:9][S:10][C:11]4[S:12][C:13]([CH2:16][NH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])=[N:14][N:15]=4)[CH2:7][S:8][C@H:3]23)=[O:65])[N:62]=1)=[O:56]