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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 272961Erstellt: 26. Oktober 2026

4-[4-(1-Isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile → 4-{4-[(1-isopropylpiperidin-4-yl)oxy]phenyl}tetrahydro-2H-pyran-4-carbothioamide

https://huagongshe.com/reaction/272961

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-[4-(1-Isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrileHCID 11500842—
EduktDiethyldithiophosphateHCID 53249491—
Produkt4-{4-[(1-isopropylpiperidin-4-yl)oxy]phenyl}tetrahydro-2H-pyran-4-carbothioamideHCID 8660190274%

Reaktionsschritte

The title compound (320 mg, 74%) was prepared from 4-[4-(1-isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile and diethyl dithiophosphate similarly to the procedure used for intermediate 50. LRMS APCI+ m/z 363 [MH]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07456164B2
Quelldatensatzuspto-grants-2008_11
ORD IDord-e82aa4813a064554b0dcb3babcd4d819
Quellennotizuspto-grants-2008_11