HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,6-Difluorobenzoyl chloride → N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,6-Difluorobenzoyl chloride | HCID 87438 | — |
| Edukt | Tyrosine ethyl ester hydrochloride | HCID 2724939 | — |
| Produkt | N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester | HCID 66843057 | — |
Reaktionsschritte
L-Tyrosine ethyl ester hydrochloride (10.0 g) was acylated with 2,6-difluorobenzoyl chloride in a similar manner as described in Example 1-(5) to give N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester (13.2 g). mp. 149-150° C.; IR (Nujol) 3424, 3277, 1721, 1660, 1624 cm−1; MS (APCI) m/z 350 (M+H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07456217B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-36aef04db34843dc9c495520e2c6bf7b |
| Quellennotiz | uspto-grants-2008_11 |