HCID 14614968, Verbindung → HCID 11024734, Verbindung

HRID 273911Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 273911
[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH:25]2[CH:16]([C:17](=[O:27])[C:18]3[C:23]([C:24]2=[O:26])=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:15][CH:14]=[CH:13]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[Cu]Cl.N1C=CC=CC=1>[CH2:1]([O:8][C:9]([NH:11][C:12]1[C:25]2[C:24](=[O:26])[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17](=[O:27])[C:16]=2[CH:15]=[CH:14][CH:13]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 1

HCID 14614968HCID 14614968, Verbindung

Produkt 1

HCID 11024734HCID 11024734, VerbindungAusbeute 88,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 62652Cuprous chlorideKatalysatorHCID 1049PyridineLösungsmittel

Versuchsvorschrift

0.47 g of 1-benzyloxycarbonylamino-1,4,4a,9a-tetrahydroanthraquinone, 6 mg of copper(I) chloride and 10 ml of pyridine were stirred at 25° C. for 30 hours under a gentle stream of air and the solution was then concentrated in vacuo. The residue was taken up in chloroform, the solution was extracted with 2N hydrochloric acid and the organic phase was concentrated in vacuo. 0.41 g of 1-benzyloxycarbonylaminoanthraquinone (86% pure; 76% of theory) was obtained.

Aufarbeitung

  1. concentrationthe solution was then concentrated in vacuo
  2. extractionthe solution was extracted with 2N hydrochloric acid
  3. concentrationthe organic phase was concentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-d963fcfe3a7549d4b179f25a147e5fff
Quelldatensatz
uspto-grants-1995_02
Patentnummer
US05387704

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