N-bromobutanimide → 1H-Pyrrole-2-carbonitrile, 1-[4-(bromomethyl)phenyl]-

Beteiligte Stoffe

Reaktionsschritte

A solution of 1-(4-methylphenyl)pyrrole-2-carbonitrile (4.9 g), N-bromosuccinimide (5.5 g) and perbenzoic acid (65 mg) in carbon tetrachloride was heated under reflux in light radiation for 2 hours. After removal of insoluble materials by filtration, the filtrate was concentrated to dryness. The residue was purified by column chromatography on silica gel to afford a colorless syrup (6.6 g, 93%).

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