HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,4-Dioxaspiro[4.5]decan-8-one → 8-(3,4-Difluorophenyl)-1,4-dioxaspiro[4.5]decan-8-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,4-Dioxaspiro[4.5]decan-8-one | HCID 567415 | — |
| Edukt | HCID 178505835 | HCID 178505835 | — |
| Produkt | 8-(3,4-Difluorophenyl)-1,4-dioxaspiro[4.5]decan-8-ol | HCID 22122104 | 42% |
Reaktionsschritte
This compound was prepared from 1,4-cyclohexanedione monoethylene ketal (15.6 g, 100 mmole) and 3,4-difluorophenyl magnesium bromide (100 mmole) in the usual manner. The crude product was crystallized from isopropyl ether to give the product (42%, mp: 118°-120° C.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05391570 |
| Quelldatensatz | uspto-grants-1995_02 |
| ORD ID | ord-4f7081b16600494da2768c7c3173e73b |
| Quellennotiz | uspto-grants-1995_02 |