Reaktionsgleichung
N1C=CC(CNCCN)=N1.C(N=C=S)C.[CH2:16]([NH:18][C:19]([NH:21][CH2:22][CH2:23][NH:24][CH2:25][C:26]1[CH:30]=[CH:29][NH:28][N:27]=1)=S)[CH3:17].[N:31]#[C:32][NH2:33].[Pb]>>[C:32]([NH:33][C:19]([NH:18][CH2:16][CH3:17])=[N:21][CH2:22][CH2:23][NH:24][CH2:25][C:26]1[CH:30]=[CH:29][NH:28][N:27]=1)#[N:31]Komponenten
5
Versuchsvorschrift
By the procedure of Example 3(b), reacting N-(3-pyrazolylmethyl)ethylenediamine with ethyl isothiocyanate, then reacting the resulting N-ethyl-N'-[2-(3-pyrazolylmethylamino)ethyl]thiourea with lead cyanamide gives N-cyano-N'-ethyl-N"-[2-(3-pyrazolylmethylamino)ethyl]guanidine. By the same procedure, using propyl isothiocyanate the corresponding N'-propyl compound is prepared. Also, by the same procedure, using 2-dimethylaminoethyl isothiocyanate, the product is N-cyano-N'-(2-dimethylaminoethyl)-N"-[2-(3-pyrazolylmethylamino)ethyl]guanidine.
Quellen und Nachweise
- ORD-Eintrag
- ord-9400006be74740d2b743a43dda1e6d5e
- Quelldatensatz
- uspto-grants-1980_09
- Patentnummer
- US04221802
Verknüpfte Notizen
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