Acetyl chloride → Benzoic acid, 3-methoxy-4-methyl-, methyl ester

HRID 275118

Reaktionsgleichung

Reaktionsgleichung von HRID 275118
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[CH3:12])[C:6]([OH:8])=[O:7].[C:13](Cl)(=O)C>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[CH3:12])[C:6]([O:8][CH3:13])=[O:7]

Komponenten

4

Edukt 2

HCID 6367Acetyl chlorideHCID 815794-Methyl-m-anisic acid

Produkt 1

HCID 591123Benzoic acid, 3-methoxy-4-methyl-, methyl esterAusbeute 98 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 3-methoxy-4-methylbenzoic acid (6.0 g.) in methanol (120 ml.) was treated with acetyl chloride (6 ml.) and stirred for 36 hours. The solution was evaporated. The residue was dissolved in methanol (100 ml.) and the solution evaporated. This procedure was repeated to give methyl 3-methoxy-4-methylbenzoate (6.34 g., 98%) as a colorless oil; NMR: 2.2(s,3H, CH3), 3.9(2s,6H, 2×OCH3), 7.1(d,1H), 7.5 (m,2H).

Aufarbeitung

  1. customThe solution was evaporated
  2. dissolutionThe residue was dissolved in methanol (100 ml.)
  3. customthe solution evaporated

Quellen und Nachweise

ORD-Eintrag
ord-51850e3273114ccbaaa1b8875901bd74
Quelldatensatz
uspto-grants-1995_02
Patentnummer
US05391758

Verknüpfte Notizen

Wird geladen…