Methyl iodide → HCID 22663158, Verbindung
Reaktionsgleichung
[C:1]([NH:9][C:10]1[CH:11]=[C:12]([C:16]2[C:25]3[C:20](=[CH:21][C:22]([O:28][CH3:29])=[C:23]([O:26][CH3:27])[CH:24]=3)[N:19]=[C:18]([NH:30][CH3:31])[N:17]=2)[CH:13]=[CH:14][CH:15]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:32]I>>[CH2:1]([N:9]([C:10]1[CH:11]=[C:12]([C:16]2[C:25]3[C:20](=[CH:21][C:22]([O:28][CH3:29])=[C:23]([O:26][CH3:27])[CH:24]=3)[N:19]=[C:18]([NH:30][CH3:31])[N:17]=2)[CH:13]=[CH:14][CH:15]=1)[CH3:32])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
Starting from 100 mg of 4-(3-benzylaminophenyl)-6,7-dimethoxy-2-methylaminoquinazoline obtained in Example 38 and 71.0 mg of methyl iodide, 35.0 mg of the title compound was obtained as a pale yellow oil in the same manner as in Example 38.
Quellen und Nachweise
- ORD-Eintrag
- ord-d335f4172960401c8a2f461d97a974de
- Quelldatensatz
- uspto-grants-2002_03
- Patentnummer
- US06352989B1