Ethanolamine → 2-Cycloheptylamino-ethanol

HRID 276332

Reaktionsgleichung

[OH:1][CH2:2][CH2:3][NH2:4].[CH:5]1(Br)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1>>[CH:5]1([NH:4][CH2:3][CH2:2][OH:1])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1

Komponenten

Edukt 2

HCID 700Ethanolamine

HCID 16992Bromocycloheptane

Produkt 1

HCID 122178912-Cycloheptylamino-ethanol

Versuchsvorschrift

2-Hydroxyethylamine was reacted with cycloheptyl bromide according to Method B2a to give N-cycloheptyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cycloheptyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-cycloheptyl-1,3-thiazolidine.

Quellen und Nachweise

ORD-Eintrag: ord-f63e4eabee7f4de98724ce9d245b45f2
Quelldatensatz: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06353006B1

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