Thionyl Chloride → N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride

HRID 276374

Reaktionsgleichung

Reaktionsgleichung von HRID 276374
[CH:1]1([CH2:6][NH:7][CH2:8][CH2:9]O)[CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:13]>>[Cl-:13].[CH:1]1([CH2:6][NH2+:7][CH2:8][CH2:9][Cl:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 18316431N-cyclopentylmethyl-N-(2-hydroxyethyl)amine

Produkt 1

HCID 18316280N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride

Versuchsvorschrift

2-Hydroxyethylamine was reacted with cyclopentylmethyl bromide according to Method B2a to give N-cyclopentylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-(cyclopentylmethyl)-1,3-thiazolidine.

Quellen und Nachweise

ORD-Eintrag
ord-25ea4c21ce9c4af1abc78cd526a1491a
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06353006B1

Verknüpfte Notizen

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