2-Methyl-4-nitrophenyl isothiocyanate → 2-(2-Methyl-4-nitrophenylimino)-3-(cyclopentylmethyl)-1,3-thiazolidine

HRID 276375

Reaktionsgleichung

Reaktionsgleichung von HRID 276375
[Cl-].[CH:2]1([CH2:7][NH2+:8][CH2:9][CH2:10]Cl)[CH2:6][CH2:5][CH2:4][CH2:3]1.[CH3:12][C:13]1[CH:18]=[C:17]([N+:19]([O-:21])=[O:20])[CH:16]=[CH:15][C:14]=1[N:22]=[C:23]=[S:24]>>[CH3:12][C:13]1[CH:18]=[C:17]([N+:19]([O-:21])=[O:20])[CH:16]=[CH:15][C:14]=1[N:22]=[C:23]1[N:8]([CH2:7][CH:2]2[CH2:6][CH2:5][CH2:4][CH2:3]2)[CH2:9][CH2:10][S:24]1

Komponenten

3

Edukt 2

HCID 1456212-Methyl-4-nitrophenyl isothiocyanateHCID 18316280N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride

Produkt 1

HCID 183161922-(2-Methyl-4-nitrophenylimino)-3-(cyclopentylmethyl)-1,3-thiazolidine

Versuchsvorschrift

2-Hydroxyethylamine was reacted with cyclopentylmethyl bromide according to Method B2a to give N-cyclopentylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cyclopentylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methyl-4-nitrophenyl isothiocyanate to give 2-(2-methyl-4-nitrophenylimino)-3-(cyclopentylmethyl)-1,3-thiazolidine.

Quellen und Nachweise

ORD-Eintrag
ord-27f621abef0947c88fc46b7e03ab51ca
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06353006B1

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