HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thionyl Chloride → (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | L-Leucinol | HCID 111307 | — |
| Edukt | 2-Ethyl-4-cyanophenyl isothiocyanate | HCID 18316102 | — |
| Produkt | (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine | HCID 178436590 | — |
Reaktionsschritte
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was reacted with SOCl2 followed by 4-cyano-2-ethylphenyl isothiocyanate according to Method C2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-3,4-diisobutyl-1,3-thiazolidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06353006B1 |
| Quelldatensatz | uspto-grants-2002_03 |
| ORD ID | ord-729bc953ecec46e080796b4cb27e7f59 |
| Quellennotiz | uspto-grants-2002_03 |