HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 22624891, Verbindung → 2-(Pyridin-3-yloxy)ethan-1-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | HCID 22624891 | HCID 22624891 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-(Pyridin-3-yloxy)ethan-1-ol | HCID 21908997 | 86% |
Reaktionsschritte
A solution of 3-(2-(tetrahydropyran-2-yloxy)ethoxy)pyridine (1.54 g, 7 mmol) in acetic acid (8 ml), THF (4 ml) and water (2 ml) was heated at 50° C. for 4 hours. The volatiles were removed by evaporation and the residue azeotroped with toluene to give 3-(2-hydroxyethoxy)pyridine (820 mg, 86%) as an off-white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06362336B1 |
| Quelldatensatz | uspto-grants-2002_03 |
| ORD ID | ord-27d37db75bc147aaac8aa4d41bb8802f |
| Quellennotiz | uspto-grants-2002_03 |