HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Imidazole-4,5-dicarboxylic acid, 4,5-dimethyl ester → 1H-Imidazole-4,5-dimethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1H-Imidazole-4,5-dicarboxylic acid, 4,5-dimethyl ester | HCID 76810 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 1H-Imidazole-4,5-dimethanol | HCID 573629 | — |
Reaktionsschritte
Reflux dimethyl 4,5 imidazole dicarboxylate (1.8 g) in THF (tetrahydrofuran) with 2.5 equivalents of LAH lithium aluminum hydride). Neutralize with NH4Cl solution and filter. Concentrate the filtrate under vacumm and extract the product with ethanol. Remove the solvent, filtrate through alumina using a THF solvent to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04587241 |
| Quelldatensatz | uspto-grants-1986_05 |
| ORD ID | ord-12483586f11b49f08bb683b241c74f50 |
| Quellennotiz | uspto-grants-1986_05 |