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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 280310Erstellt: 26. Oktober 2026

3-(Trifluoromethyl)phenylglyoxal → N-(3-(4-Methylphenyl)propyl)-2-hydroxy-2-(3-trifluoromethylphenyl)ethanamine

https://huagongshe.com/reaction/280310

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(Trifluoromethyl)phenylglyoxalHCID 2783284—
Edukt3-(4-Methylphenyl)propan-1-amineHCID 12564270—
ProduktN-(3-(4-Methylphenyl)propyl)-2-hydroxy-2-(3-trifluoromethylphenyl)ethanamineHCID 23322159—

Reaktionsschritte

The title compound was prepared in the manner described in Example 9 using 3-trifluoromethylphenylglyoxal and 3-(4-methylphenyl)propanamine. Recrystallization of the chromatographed material from hexane gave the title compound m.p. 96-98. τ(CDCl3) 8.0-8.5 (2H, m), 7.7 (3H, s), 7.0-7.5 (6H, m+2H, disappears with D2O), 5.3 (1H, dd), 2.9 (4H, s), 2.3-2.7 (4H, m).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04588749
Quelldatensatzuspto-grants-1986_05
ORD IDord-a43d5886af2b4183ae5193bb0f0e2f07
Quellennotizuspto-grants-1986_05