2-Methoxyaniline → HCID 23338370, Verbindung

HRID 28039Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 28039
[CH3:1][O:2][C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].C(=O)([O-])[O-].[Na+].[Na+].Br[CH2:17][CH:18]1[O:22][CH:21]([CH2:23][CH2:24][CH3:25])[CH2:20][O:19]1>>[CH2:23]([CH:21]1[CH2:20][O:19][CH:18]([CH2:17][NH:5][C:4]2[CH:6]=[CH:7][CH:8]=[CH:9][C:3]=2[O:2][CH3:1])[O:22]1)[CH2:24][CH3:25]

Komponenten

4

Edukt 3

HCID 70002-MethoxyanilineHCID 10340Sodium CarbonateHCID 233383912-Bromomethyl-4-propyl-1,3-dioxolane

Produkt 1

HCID 23338370HCID 23338370, Verbindung

Versuchsvorschrift

2-Methoxyaniline (0.05 mole) and sodium carbonate (30 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Bromomethyl-4-propyl-1,3-dioxolane (0.55 mole) is slowly added and the reaction mixture is heated at reflux for a period of about 1 hour. After this time the reaction mixture is filtered and additional sodium carbonate (5 grams) is added to the filtrate. The mixture is then distilled under reduced pressure to yield the desired product N-(4-propyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline.

Aufarbeitung

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperaturethe reaction mixture is heated
  4. temperatureat reflux for a period of about 1 hour
  5. filtrationAfter this time the reaction mixture is filtered
  6. additionadditional sodium carbonate (5 grams) is added to the filtrate
  7. distillationThe mixture is then distilled under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-24d24d89ab8b4c48a8a7cd14df8e53d6
Quelldatensatz
uspto-grants-1980_09
Patentnummer
US04225335

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