Hydrochloric Acid → HCID 53739261, Verbindung

HRID 280614Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 280614
[CH3:1][C:2]1[S:6][C:5]2[C:7]([C:11]([OH:13])=[O:12])=[CH:8][CH:9]=[CH:10][C:4]=2[CH:3]=1.Cl.[CH3:15]O>>[CH3:15][O:12][C:11]([C:7]1[C:5]2[S:6][C:2]([CH3:1])=[CH:3][C:4]=2[CH:10]=[CH:9][CH:8]=1)=[O:13]

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 126239032-Methyl-1-benzothiophene-7-carboxylic acid

Produkt 1

HCID 53739261HCID 53739261, Verbindung

Versuchsvorschrift

A solution of 2-methylbenzo[b]thiophene-7-carboxylic acid (5.1 g) in methanol (100 ml) was saturated with hydrogen chloride and then heated under reflux for 18 hours. The solution was evaporated and the residue was dissolved in ether. The ether solution was washed with sodium carbonate solution and dried (Na2SO4). Evaporation of the ether gave 2-methylbenzo[b]thiophene-7-carboxylic acid methyl ester (4.7 g), m.p. 48°-49°.

Aufarbeitung

  1. temperatureheated
  2. temperatureunder reflux for 18 hours
  3. customThe solution was evaporated
  4. dissolutionthe residue was dissolved in ether
  5. washThe ether solution was washed with sodium carbonate solution
  6. dry with materialdried (Na2SO4)
  7. customEvaporation of the ether

Quellen und Nachweise

ORD-Eintrag
ord-6f87be024b13420eb8893aea4f40d0c7
Quelldatensatz
uspto-grants-1986_05
Patentnummer
US04590200

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