Methanol → Salicylic acid, 4-nitro-, methyl ester

HRID 280832

Reaktionsgleichung

Reaktionsgleichung von HRID 280832
[OH:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:14]O>S(=O)(=O)(O)O>[OH:1][C:2]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH3:14])=[O:5]

Komponenten

4

Edukt 2

HCID 887MethanolHCID 692664-Nitrosalicylic acid

Produkt 1

HCID 139539Salicylic acid, 4-nitro-, methyl ester

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

2-hydroxy-4-nitrobenzoic acid (25 g) was dissolved in 100 ml of methanol and sulfuric acid (11 ml, density 1.84). The solution was boiled for 24 hrs, whereupon it was poured onto ice water and extracted with chloroform. The chloroform phase was shaken against sodium hydrogen carbonate solution, dried with magnesium sulfate and evaporated. The product was crystallized from methanol. Yield: 21 g.

Aufarbeitung

  1. additionwas poured onto ice water
  2. extractionextracted with chloroform
  3. dry with materialdried with magnesium sulfate
  4. customevaporated
  5. customThe product was crystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-5703b5d6de4b4f1faa1fd8a3a014c4fe
Quelldatensatz
uspto-grants-1986_05
Patentnummer
US04591584

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