Dichloromethane → (1-[4-(2-Acetylamino-4-methyl-thiazol-5-yl)-5-bromo-thiophene-2-sulfonyl]-piperidin-4-yl}-methyl-carbamic acid tert-butyl ester

HRID 281601Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 281601
[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7](-[c:11]2[cH:12][c:13]([S:17](=[O:18])(=[O:19])[Cl:20])[s:14][c:15]2[Br:16])[c:8]([CH3:10])[n:9]1.[C:28]([CH3:29])([CH3:30])([CH3:31])[O:32][C:33]([N:34]([CH:35]1[CH2:36][CH2:37][NH:38][CH2:39][CH2:40]1)[CH3:41])=[O:42].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:43][CH2:44][Cl:45]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7](-[c:11]2[cH:12][c:13]([S:17](=[O:18])(=[O:19])[N:38]3[CH2:37][CH2:36][CH:35]([N:34]([C:33]([O:32][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:42])[CH3:41])[CH2:40][CH2:39]3)[s:14][c:15]2[Br:16])[c:8]([CH3:10])[n:9]1

Komponenten

5

Edukt 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27568064-N-Boc-4-N-Methyl-aminopiperidineHCID 866231464-[2-(Acetylamino)-4-methyl-1,3-thiazol-5-yl]-5-bromothiophene-2-sulfonylchloride

Produkt 1

HCID 86652444(1-[4-(2-Acetylamino-4-methyl-thiazol-5-yl)-5-bromo-thiophene-2-sulfonyl]-piperidin-4-yl}-methyl-carbamic acid tert-butyl ester

Quellen und Nachweise

ORD-Eintrag
ord-7abc834e6caa4fb8a9ca937ccd349dca
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

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