HCID 68988422, Verbindung → HCID 68988417, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:16])=[C:6]([C:8]2[CH:13]=[C:12](Cl)[N:11]=[C:10]([NH2:15])[N:9]=2)[CH:7]=1.[CH3:17][O:18][C:19](=[O:34])[CH2:20][CH2:21][C:22]1[O:23][CH:24]=[C:25]([C:27]2[CH:32]=[CH:31][C:30]([NH2:33])=[CH:29][CH:28]=2)[N:26]=1>>[CH3:17][O:18][C:19](=[O:34])[CH2:20][CH2:21][C:22]1[O:23][CH:24]=[C:25]([C:27]2[CH:32]=[CH:31][C:30]([NH:33][C:12]3[CH:13]=[C:8]([C:6]4[CH:7]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=4[CH3:16])[N:9]=[C:10]([NH2:15])[N:11]=3)=[CH:29][CH:28]=2)[N:26]=1Komponenten
3
Versuchsvorschrift
Following the method described in Example 26, 4-(5-chloro-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 3-[4-(4-amino-phenyl)-oxazol-2-yl]-propionic acid methyl ester provided 3-(4-{4-[2-amino-6-(5-chloro-2-methyl-phenyl)-pyrimidin-4-ylamino]-phenyl}-oxazol-2-yl)-propionic acid methyl ester.
Quellen und Nachweise
- ORD-Eintrag
- ord-c9f5a13bae9941b3b5f1b51e77402a04
- Quelldatensatz
- uspto-grants-2008_09