Methanol → Pexmetinib

Reaktionsgleichung

[BH4-:42].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7](-[c:35]2[cH:36][cH:37][c:38]([CH3:41])[cH:39][cH:40]2)[c:8]([NH:10][C:11](=[O:12])[NH:13][CH2:14][c:15]2[c:16]([O:22][c:23]3[cH:24][c:25]4[cH:26][n:27][n:28]([CH2:32][CH:33]=[O:34])[c:29]4[cH:30][cH:31]3)[cH:17][cH:18][c:19]([F:21])[cH:20]2)[cH:9]1.[CH3:44][OH:45].[Na+:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7](-[c:35]2[cH:36][cH:37][c:38]([CH3:41])[cH:39][cH:40]2)[c:8]([NH:10][C:11](=[O:12])[NH:13][CH2:14][c:15]2[c:16]([O:22][c:23]3[cH:24][c:25]4[cH:26][n:27][n:28]([CH2:32][CH2:33][OH:34])[c:29]4[cH:30][cH:31]3)[cH:17][cH:18][c:19]([F:21])[cH:20]2)[cH:9]1