3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → tert-Butyl {4-[[5-(6-amino-pyridin-3-yl)-2-methoxy-benzyl]-(3-chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl)-amino]-cyclohexyl}-methyl-carbamate

Reaktionsgleichung

[Cl:33][c:34]1[c:35]2[c:36]([s:37][c:38]1[C:39](=[O:40])[Cl:41])[c:42]([F:47])[cH:43][cH:44][c:45]2[F:46].[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:31][CH3:32])[c:12]([CH2:13][NH:14][CH:15]3[CH2:16][CH2:17][CH:18]([N:21]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH3:29])[CH2:19][CH2:20]3)[cH:30]2)[cH:6][n:7]1>>[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([O:31][CH3:32])[c:12]([CH2:13][N:14]([CH:15]3[CH2:16][CH2:17][CH:18]([N:21]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH3:29])[CH2:19][CH2:20]3)[C:39]([c:38]3[c:34]([Cl:33])[c:35]4[c:36]([s:37]3)[c:42]([F:47])[cH:43][cH:44][c:45]4[F:46])=[O:40])[cH:30]2)[cH:6][n:7]1