Propane-2-sulfonamide → 3-Methyl-4-(propane-2-sulfonylamino)-benzofuran-2-carboxylic acid ethyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Propane-2-sulfonamide	HCID 3549191	—
Edukt	3-Methyl-4-trifluoromethanesulfonyloxy-benzofuran-2-carboxylic acid ethyl ester	HCID 86599026	—
Produkt	3-Methyl-4-(propane-2-sulfonylamino)-benzofuran-2-carboxylic acid ethyl ester	HCID 68713474	23%

Reaktionsschritte

Coupling of isopropylsulfonamide with 3-methyl-4-trifluoromethanesulfonyloxy-benzofuran-2-carboxylic acid ethyl ester was carried out according to Example 36, Step 1 to give 3-methyl-4-(propane-2-sulfonylamino)-benzofuran-2-carboxylic acid ethyl ester in 23% yield. 1H NMR (400 MHz, CDCl3) δ ppm 1.4 (t, J=6.4 Hz, 9 H) 2.9 (t, 3 H) 3.5 (m, 1 H) 4.5 (q, J=7.1 Hz, 2 H) 6.6 (s, 1 H) 7.4 (m, 3 H).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07420001B2
Quelldatensatz	uspto-grants-2008_09
ORD ID	ord-b95a7ebe74064e24a5a8ee037cf564da
Quellennotiz	uspto-grants-2008_09