2-Amino-4-chlorobenzenethiol → Ethyl 5-chloro-1,3-benzothiazole-2-carboxylate

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To 2-amino-4-chloro-benzenethiol (1 g) was added ethyl triethoxyacetate (3 eq). The mixture was stirred at 110° C. overnight. The reaction mixture was cooled and triturated with hexane. Filtration gave 392 mg of 5-chloro-benzothiazole-2-carboxylic acid ethyl ester as a white solid.

Herkunft & Nachweise