HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Iodine → 3-Iodo-4-methylbenzyl alcohol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Iodine | HCID 807 | — |
| Edukt | 3-Iodo-4-methylbenzoic acid | HCID 621640 | — |
| Edukt | Sodium borohydride | HCID 4311764 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-Iodo-4-methylbenzyl alcohol | HCID 5166798 | — |
Reaktionsschritte
A mixture of 1.0 mmol of 3-iodo-4-methylbenzoic acid and 1.2 mmol of NaBH4 in 4 mL of anhydrous THF was stirred for 30 min and then 0.5 mmol of iodine in 2.0 mL of THF at 5° C. was added. After stirring for 2 h the mixture was processed by extraction to provide 3-iodo-4-methylbenzyl alcohol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05731432 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-2717ca80753c46a39e12e91d075435b5 |
| Quellennotiz | uspto-grants-1998_03 |