Tetrahydrofuran → [2-Chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]cyclopentylamine

HRID 297753

Reaktionsgleichung

[Br:1][c:2]1[c:3]([NH:9][CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:22]([CH3:23])[O:24][CH:25]([C:26]#[CH:27])[O:28][CH2:29][CH3:30].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[Cu:36][I:37]>>[c:2]1([C:27]#[C:26][CH:25]([O:24][CH2:22][CH3:23])[O:28][CH2:29][CH3:30])[c:3]([NH:9][CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1

Komponenten

Edukt 5

HCID 8028Tetrahydrofuran

HCID 8471Triethylamine

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 662853,3-Diethoxypropyne

HCID 442482475-Bromo-2-chloro-N-cyclopentyl-4-pyrimidinamine

Produkt 1

HCID 58315397[2-Chloro-5-(3,3-diethoxy-prop-1-ynyl)-pyrimidin-4-yl]cyclopentylamine

Quellen und Nachweise

ORD-Eintrag: ord-cbee5552906f4e11a866f12da6cc1561
Quelldatensatz: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Verknüpfte Notizen

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