Reaktionsgleichung
[NH2:1][C:2]1[C:7]([C:8]([C:10]2[CH:15]=[C:14]([F:16])[CH:13]=[CH:12][C:11]=2[O:17][CH3:18])=[O:9])=[CH:6][CH:5]=[C:4](Cl)[N:3]=1.[CH2:20]([O:22][C:23]([N:25]1[CH2:30][CH2:29][CH:28]([NH2:31])[CH2:27][CH2:26]1)=[O:24])[CH3:21]>>[CH2:20]([O:22][C:23]([N:25]1[CH2:26][CH2:27][CH:28]([NH:31][C:4]2[CH:5]=[CH:6][C:7]([C:8](=[O:9])[C:10]3[CH:15]=[C:14]([F:16])[CH:13]=[CH:12][C:11]=3[O:17][CH3:18])=[C:2]([NH2:1])[N:3]=2)[CH2:29][CH2:30]1)=[O:24])[CH3:21]Komponenten
3
Versuchsvorschrift
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-phenyl)-methanone (Example 19) and ethyl-4-amino-1-piperidine carboxylate (Aldrich 96) using the procedure described in Step B. Example 6. HRMS, observed: 417.1938, Calcd for (M+H)+: 417.1933.
Quellen und Nachweise
- ORD-Eintrag
- ord-87c7e9c2643140cc8dad5ec1a1455045
- Quelldatensatz
- uspto-grants-2008_09
- Patentnummer
- US07423051B2
Verknüpfte Notizen
Wird geladen…