HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Propyl chloroformate → 4-[6-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid propyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Propyl chloroformate | HCID 7998 | — |
| Edukt | [4-Amino-2-(piperidin4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt | HCID 21070627 | — |
| Produkt | 4-[6-Amino-5-(5-fluoro-2-methoxy-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid propyl ester | HCID 11711671 | — |
Reaktionsschritte
The title compound was prepared from [4-amino-2-(piperidin4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone trifluoroacetic acid salt (Example 22) and 1-propyl chloroformate (Aldrich 98%) using the procedure described in Example 24. HRMS, observed: 431.2095, Calcd for (M+H)+: 431.2089.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07423051B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-c0687cd1d52d4fe6a285679a6f20e484 |
| Quellennotiz | uspto-grants-2008_09 |