HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromo-1-(4-fluorophenyl)ethan-1-one → (RS)-2-[2-(4-Fluoro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Bromo-1-(4-fluorophenyl)ethan-1-one | HCID 96749 | — |
| Edukt | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| Produkt | (RS)-2-[2-(4-Fluoro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester | HCID 86629009 | 96,9% |
Reaktionsschritte
The title compound (3.83 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (2.54 g) and 2-bromo-4′-fluoroacetophenone (2.26 g) according to the method of description 36.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07423052B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-bfa1eb39978b4e89b76325180d974536 |
| Quellennotiz | uspto-grants-2008_09 |