1-Isopropylpiperazine → (2-Chloro-pyridin-4-yl)-(4-isopropyl-piperazin-1-yl)-methanone

HRID 30466

Reaktionsgleichung

[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][N:10]=1)[C:5]([OH:7])=O.[CH:11]([N:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1)([CH3:13])[CH3:12]>>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]([N:17]2[CH2:18][CH2:19][N:14]([CH:11]([CH3:13])[CH3:12])[CH2:15][CH2:16]2)=[O:7])[CH:8]=[CH:9][N:10]=1

Komponenten

Edukt 2

HCID 780131-Isopropylpiperazine

HCID 2369852-Chloroisonicotinic acid

Produkt 1

HCID 43420916(2-Chloro-pyridin-4-yl)-(4-isopropyl-piperazin-1-yl)-methanone

Versuchsvorschrift

The title compound was prepared in a manner similar to that described in Step A of Example 9 using 2-chloro-isonicotinic acid and 1-isopropyl-piperazine.

Quellen und Nachweise

ORD-Eintrag: ord-68c700f194b54a8e93b50d98f3f94d99
Quelldatensatz: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07423147B2

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