Hydrochloric Acid → Ethanamine, 2-(4-fluorophenoxy)-, hydrochloride (1:1)

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Next, to a solution of [2-(4-fluorophenoxy)ethyl]carbamic acid tert-butyl ester (7.0 g, 27.4 mmol) in dioxane (20 mL) cooled in an ice bath was added 4N—HCl in dioxane (100 mL) dropwise. The mixture was stirred at 0° C. for 2 hours, and at room temperature for 16 hours. The precipitates were filtered, washed with diethylether, and dried under reduced pressure to yield 2-(4-fluorophenoxy)ethylamine HCl salt (4.24 g, 80.7% yield).

Herkunft & Nachweise