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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 31009Erstellt: 25. Oktober 2026

2,2,3,3,3-Pentafluoropropylamine → N-[(S)-5-(2-Benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-fluoro-2-methyl-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide

https://huagongshe.com/reaction/31009

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,2,3,3,3-PentafluoropropylamineHCID 79002—
EduktN-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-fluoro-2-methyl-malonamic acidHCID 58972471—
ProduktN-[(S)-5-(2-Benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-fluoro-2-methyl-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamideHCID 58972480—

Reaktionsschritte

Using N—[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-fluoro-2-methyl-malonamic acid and 2,2,3,3,3-pentafluoropropylamine, the title compound was prepared in the same manner as described for example 1c. Whites solid. (64%). MS: m/e=608(M+H+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07425551B2
Quelldatensatzuspto-grants-2008_09
ORD IDord-c8002b15c98d426585e3f1a5eaf5e11b
Quellennotizuspto-grants-2008_09