Methylamine → 1-Isobutyl-3-methylthiourea

HRID 31064

Reaktionsgleichung

Reaktionsgleichung von HRID 31064
[CH3:1][NH2:2].[CH2:3]([N:7]=[C:8]=[S:9])[CH:4]([CH3:6])[CH3:5]>>[CH2:3]([NH:7][C:8]([NH:2][CH3:1])=[S:9])[CH:4]([CH3:6])[CH3:5]

Komponenten

3

Edukt 2

HCID 6329MethylamineHCID 68960Isobutyl isothiocyanate

Produkt 1

HCID 155682431-Isobutyl-3-methylthioureaAusbeute 98,2 %

Versuchsvorschrift

Methylamine (2M in methanol, 20.0 mL, 40.2 mmol) was added dropwise to isobutylisothiocyanate (2.00 mL, 16.5 mmol) during 15 minutes at room temperature. The reaction mixture was heated to reflux for 3.5 h and the solvent was evaporated off to give the title compound (2.37 g, 98%) as a colourless oil.

Aufarbeitung

  1. temperatureThe reaction mixture was heated
  2. temperatureto reflux for 3.5 h
  3. customthe solvent was evaporated off

Quellen und Nachweise

ORD-Eintrag
ord-daba692c6a114204a87d5a67bd05525c
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07425560B2

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