HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide → 6-Methyl-4'-(5-pyrrolidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid cyclopropylamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 21914577 | — |
| Edukt | 2-(4-Iodophenyl)-5-pyrrolidin-1-ylmethyl-[1,3,4]oxadiazole | HCID 69316099 | — |
| Produkt | 6-Methyl-4'-(5-pyrrolidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid cyclopropylamide | HCID 10476224 | — |
Reaktionsschritte
Example 12 was prepared from 2-(4-iodophenyl)-5-pyrrolidin-1-ylmethyl-[1,3,4]oxadiazole (Intermediate 8) and N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)benzamide (Intermediate 17).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425555B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-80b509f26f7c40c5acba7d387eca0eda |
| Quellennotiz | uspto-grants-2008_09 |