5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazole → 6-Methyl-4'(3-methyl-[1,2,4]oxadiazol-5-yl)biphenyl-3-carboxylic acid [1,3,4]thiadiazol-2-ylamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5-(4-Iodophenyl)-3-methyl-1,2,4-oxadiazole	HCID 19703116	—
Edukt	4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-([1,3,4]thiadiazol-2-yl)-benzamide	HCID 58656532	—
Lösungsmittel	Dimethylformamide	HCID 6228	—
Produkt	6-Methyl-4'(3-methyl-[1,2,4]oxadiazol-5-yl)biphenyl-3-carboxylic acid [1,3,4]thiadiazol-2-ylamide	HCID 10249016	—

Reaktionsschritte

Example 27 was prepared using 5-(4-iodophenyl)-3-methyl-[1,2,4]oxadiazole (Intermediate 12) and 4-methyl-3-(4,4,5,5, -tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-([1,3,4]thiadiazol-2-yl)-benzamide (Intermediate 23) using DMF as the solvent.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07425555B2
Quelldatensatz	uspto-grants-2008_09
ORD ID	ord-7cfa817061d94cf982197f31a48d9bbf
Quellennotiz	uspto-grants-2008_09