HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole → 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid (3-morpholin-4yl-phenyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole | HCID 676569 | — |
| Edukt | 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide | HCID 59791521 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid (3-morpholin-4yl-phenyl)-amide | HCID 10049619 | — |
Reaktionsschritte
Example 36 was prepared using 2-(4-iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and 4-methyl-N-(3-morpholin-4-phenyl)-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (Intermediate 5) with propan-2-ol as the solvent.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425555B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-a4b8d48e0080424d84f52a79d258df2c |
| Quellennotiz | uspto-grants-2008_09 |