2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole → 6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid thiazol-2-ylamide

https://huagongshe.com/de/reaction/31465

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-(4-Iodophenyl)-5-methyl-[1,3,4]oxadiazole	HCID 676569	—
Edukt	4-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(thiazol-2-yl)-benzamide	HCID 21914517	—
Edukt	4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamide	HCID 86604696	—
Lösungsmittel	Isopropanol	HCID 3776	—
Produkt	6-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid thiazol-2-ylamide	HCID 10090936	—

Reaktionsschritte

Example 38 was prepared using 2-(4-iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and 4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-N-(thiazol-2-yl)-benzamide (Intermediate 22) with propan-2-ol as the solvent.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07425555B2
Quelldatensatz	uspto-grants-2008_09
ORD ID	ord-2694e2157cdf459d9a5f59f9b3c32dea
Quellennotiz	uspto-grants-2008_09