HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → Pravastatin
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Phosphoric Acid | HCID 1004 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Mevinic Acid | HCID 446154 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | Pravastatin | HCID 54687 | — |
Reaktionsschritte
Analysis of the starting compactin by HPLC using a Waters column RP-18 (5 m, 2.1×150 mm) with a mobile phase of (a) 0.1% phosphoric acid and the pH adjusted with 25% NaOH and (b) a mixture of distilled water and acetonitrile (1:9). The column was run for 50 min at 40° C. using a detection wavelength of 240 nm. The amount of compactin was determined using a standardized solution of 10 mg of compactin and 10 mg compactin ammonium salt.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425644B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-553594d1644946f187991e86e96ab4fa |
| Quellennotiz | uspto-grants-2008_09 |