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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 31526Erstellt: 25. Oktober 2026

Water → Pravastatin

https://huagongshe.com/reaction/31526

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktWaterHCID 962—
EduktPhosphoric AcidHCID 1004—
EduktSodium HydroxideHCID 14798—
EduktMevinic AcidHCID 446154—
LösungsmittelAcetonitrileHCID 6342—
ProduktPravastatinHCID 54687—

Reaktionsschritte

Analysis of the starting compactin by HPLC using a Waters column RP-18 (5 m, 2.1×150 mm) with a mobile phase of (a) 0.1% phosphoric acid and the pH adjusted with 25% NaOH and (b) a mixture of distilled water and acetonitrile (1:9). The column was run for 50 min at 40° C. using a detection wavelength of 240 nm. The amount of compactin was determined using a standardized solution of 10 mg of compactin and 10 mg compactin ammonium salt.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07425644B2
Quelldatensatzuspto-grants-2008_09
ORD IDord-553594d1644946f187991e86e96ab4fa
Quellennotizuspto-grants-2008_09