5-Benzyloxy-2,2-dimethyl-1,3-dioxane → 2-(Phenylmethoxy)-1,3-propanediol

HRID 31603

Reaktionsgleichung

Reaktionsgleichung von HRID 31603
[CH2:1]([O:8][CH:9]1[CH2:14][O:13]C(C)(C)[O:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO>[CH2:1]([O:8][CH:9]([CH2:10][OH:11])[CH2:14][OH:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 1

HCID 203648895-Benzyloxy-2,2-dimethyl-1,3-dioxane

Produkt 1

HCID 2035672-(Phenylmethoxy)-1,3-propanediolAusbeute 94 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a methanol (50 ml) solution of the 5-(benzyloxy)-2,2-dimethyl-1,3-dioxane (6.5 g, 29.2 mmol) obtained in the step (9b), DOWEX® 50W-X8 (5 g) was added and stirred at room temperature. After 2 hours, the reaction mixture was filtered and concentrated to obtain the title compound (5.0 g, 93.8%) as a colorless oil.

Aufarbeitung

  1. addition(5 g) was added
  2. filtrationthe reaction mixture was filtered
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-ec108d8ddcc040d39d8ce9b503d6cacb
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07425634B2

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