Cyclopentanone → 6,10-Dioxaspiro[4.5]dec-8-ylmethanol

Reaktionsgleichung

[OH:1][CH2:2][CH:3]([CH2:6][OH:7])[CH2:4][OH:5].[C:8]1(=O)[CH2:12][CH2:11][CH2:10][CH2:9]1>>[CH2:8]1[C:12]2([O:5][CH2:4][CH:3]([CH2:6][OH:7])[CH2:2][O:1]2)[CH2:11][CH2:10][CH2:9]1

Komponenten

Edukt 2

HCID 8452Cyclopentanone

HCID 78432Trimethylolmethane

Produkt 1

HCID 597925846,10-Dioxaspiro[4.5]dec-8-ylmethanolAusbeute 87 %

Versuchsvorschrift

The same procedure as in the step (7a) of Example 7 was repeated using 2-(hydroxymethyl)-1,3-propanediol and cyclopentanone to obtain the title compound (2.8 g, yield: 87%) as yellow oil.

Quellen und Nachweise

ORD-Eintrag: ord-34ff411fa72c4faba1c55b4737b91356
Quelldatensatz: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07425634B2

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