HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Solketal → HCID 178431368, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Solketal | HCID 7528 | — |
| Edukt | 4-Chloro-2,3-dimethyl-1-oxidopyridin-1-ium | HCID 9877446 | — |
| Edukt | 2-(((4-((2,2-Dimethyl-1,3-dioxan-5-yl)methoxy)-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66775847 | — |
| Edukt | HCID 178505474 | HCID 178505474 | — |
| Produkt | HCID 178431368 | HCID 178431368 | 14,1% |
Reaktionsschritte
The same procedure as in the step (10b) of Example 10 and the step (14b) of Example 14, the step (5f) of Example 5, the steps (11h) and (11i) of Example 11 was repeated using solketal, 4-chloro-2,3-dimethylpyridine 1-oxide, and 5-fluoro-1H-benzimidazole-2-thiol to obtain the title compound (210 mg, yield: 14.1%) as a white solid. Note that methanol was used as a solvent instead of ethanol in the same operation as in the step (5f).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425634B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-a11e91989b544cc486de35037d86b48b |
| Quellennotiz | uspto-grants-2008_09 |