HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Trifluoromethyl)benzoyl chloride → 6-{[2-({5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| Edukt | 6-Chloro-3-pyridinecarbonitrile | HCID 5152094 | — |
| Edukt | Chir-98023 | HCID 9847557 | — |
| Produkt | 6-{[2-({5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrile | HCID 22142493 | — |
Reaktionsschritte
b 6-{[2-({5-imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrile was prepared from 4-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07425557B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-5644389144a8421785b01900d6826ba8 |
| Quellennotiz | uspto-grants-2008_09 |