1,3-Dichloroacetone → HCID 22009623, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([C:7]([NH2:9])=[O:8])[S:5][CH:6]=1.[Cl:10][CH2:11][C:12]([CH2:14]Cl)=O>>[Cl:10][CH2:11][C:12]1[N:9]=[C:7]([C:4]2[S:5][CH:6]=[C:2]([Cl:1])[CH:3]=2)[O:8][CH:14]=1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Reference Example 47, 4-chloro-2-thiophenecarboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(4-chloro-2-thienyl)oxazole. The yield was 48%. Recrystallization from diethyl ether-hexane gave colorless needles, mp 72-73° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-3f8411a85f08443b996bec10198c03f3
- Quelldatensatz
- uspto-grants-2001_04
- Patentnummer
- US06211215B1
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