(4-Ethylamino-2-phenylamino-pyrimidin-5-yl)methanol → 4-Ethylamino-2-phenylamino-pyrimidine-5-carbaldehyde

Beteiligte Stoffe

Reaktionsschritte

To a solution of (4-ethylamino-2-phenylamino-pyrimidin-5-yl)methanol (173 mg, 0.71 mmol) in 15 mL of chloroform was added manganese oxide (600 mg, 6.89 mmol). After stirring at room temperature overnight, the mixture was filtered through a pad of Celite, washing with chloroform. The filtrate was concentrated in vacuo to give 170 mg (99%) of 4-ethylamino-2-phenylamino-pyrimidine-5-carbaldehyde; mp 155°-157° C.

Herkunft & Nachweise