HCID 4065946, Verbindung → 3-(4-(Benzyloxy)-3-methoxyphenyl)propan-1-ol
Reaktionsgleichung
[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][C:12]([CH:13]=[CH:14][C:15](OCC)=[O:16])=[CH:11][C:10]=1[O:22][CH3:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][C:12]([CH2:13][CH2:14][CH2:15][OH:16])=[CH:11][C:10]=1[O:22][CH3:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Reference Example 82, ethyl 4-benzyloxy-3-methoxycinnamate was subjected to reduction with lithium aluminum hydride to obtain 3-(4-benzyloxy-3-methoxyphenyl)propanol. The yield was 56%. Recrystallization from ethyl acetate-hexane gave colorless prisms, 57-58° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-63bf6bfc321c44ce81df430c711d3926
- Quelldatensatz
- uspto-grants-2001_04