Aluminium lithium hydride → 3-(3-Chloro-4-methoxymethoxyphenyl)propanol
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:12][CH2:13][C:14](OCC)=[O:15])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][O:10][CH3:11].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:12][CH2:13][CH2:14][OH:15])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][O:10][CH3:11]Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Reference Example 82, ethyl 3-(3-chloro-4-methoxymethoxyphenyl)propionate was subjected to reduction with lithium aluminum hydride to obtain 3-(3-chloro-4-methoxymethoxyphenyl)propanol as an oil. The yield was 97%.
Quellen und Nachweise
- ORD-Eintrag
- ord-7eb7a663804f46d8b3cc3fa07f3cfc0e
- Quelldatensatz
- uspto-grants-2001_04
- Patentnummer
- US06211215B1
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