Imidazole → HCID 22009792, Verbindung
Reaktionsgleichung
CS(O[CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[N:17]=[C:18](/[CH:21]=[CH:22]/[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[O:19][CH:20]=2)=[CH:10][CH:9]=1)(=O)=O.[NH:29]1[CH:33]=[CH:32][N:31]=[CH:30]1>>[N:29]1([CH2:6][CH2:7][C:8]2[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]3[N:17]=[C:18](/[CH:21]=[CH:22]/[C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)[O:19][CH:20]=3)=[CH:10][CH:9]=2)[CH:33]=[CH:32][N:31]=[CH:30]1Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Working Example 25, 2-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]ethyl methanesulfonate was allowed to react with imidazole to give 4-[4-[2-(1-imidazolyl)ethyl]phenoxymethyl]-2-[(E)-2-phenylethenyl]oxazole. The yield was 38%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 165-166° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-291d42b2ce96485980f2b86ea549d35e
- Quelldatensatz
- uspto-grants-2001_04