4-(Chloromethyl)-2-(thiophen-2-yl)-1,3-oxazole → 4-[3-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(2-thienyl)oxazole

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(Chloromethyl)-2-(thiophen-2-yl)-1,3-oxazole	HCID 2529531	—
Edukt	1-[3-(3-Hydroxyphenyl)propyl]imidazole	HCID 22009809	—
Produkt	4-[3-[3-(1-Imidazolyl)propyl]phenoxymethyl]-2-(2-thienyl)oxazole	HCID 22009800	78%

Reaktionsschritte

In substantially the same manner as in Working Example 72, 1-[3-(3-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(2-thienyl)oxazole to give 4-[3-[3-(1-imidazolyl)propyl]phenoxymethyl]-2-(2-thienyl)oxazole, oily substance. The yield was 78%.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06211215B1
Quelldatensatz	uspto-grants-2001_04
ORD ID	ord-438c560d72d544f8aaa185dace7518f4
Quellennotiz	uspto-grants-2001_04